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N-Methyl-2-pyrrolidone (NMP) is an organic compound consisting of a 5-membered lactam. It is a colorless liquid, although impure samples can appear yellow. It is miscible with water and with most common organic solvents. It also belongs to the class of dipolar aprotic solvents such as dimethylformamide and dimethyl sulfoxide.
2-Pyrrolidone itself is used in inkjet cartridges. [5] A variety of pharmaceutical drugs are 2-pyrrolidone derivatives, including cotinine, doxapram, povidone, and ethosuximide, and the racetams. The chemical is an intermediate in the production of the polyvinylpyrrolidone precursor vinylpyrrolidone. [3]
Pyrrolidine, also known as tetrahydropyrrole, is an organic compound with the molecular formula (CH 2) 4 NH. It is a cyclic secondary amine , also classified as a saturated heterocycle . It is a colourless liquid that is miscible with water and most organic solvents.
The Hantzsch pyrrole synthesis is the reaction of β-ketoesters (1) with ammonia (or primary amines) and α-haloketones (2) to give substituted pyrroles (3). [ 13 ] [ 14 ] The Hantzsch pyrrole synthesis
Racetams are 2-pyrrolidone derivatives and may sometimes be referred to simply as pyrrolidones (2-oxopyrrolidines). [1] Many, but not all, specifically have a 2-oxo-1-pyrrolidine acetamide nucleus, which is the chemical structure of piracetam. Racetams are cyclic derivatives of the inhibitory neurotransmitter γ-aminobutyric acid (GABA). [2]
It is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene. [2] It is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The NVP monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives. [2]
This page was last edited on 12 November 2012, at 01:46 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
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