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One study suggests that saw palmetto may help block the activity of 5-alpha reductase — as noted, this is the enzyme that converts testosterone into DHT. Saw palmetto might also reduce the ...
Researchers believe that men affected by androgenetic alopecia tend to have higher levels of the 5-alpha-reductase enzyme, which converts testosterone into DHT, as well as an increased level of ...
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This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...
[14] [35] Like spironolactone, flutamide is typically only used by women. [36] Bicalutamide is another option for the treatment of female pattern hair loss. [37] [38] [39] It has a far lower risk of liver toxicity than flutamide and is said to have an excellent safety profile.
Thus, inhibition results in decreased amounts of DHT. Because of this, slight elevations in testosterone and estradiol levels occur. [36] The 5α-reductase reaction is a rate-limiting step in the testosterone reduction and involves the binding of NADPH to the enzyme followed by the substrate. [4] [37] Substrate + NADPH + H + → 5α-substrate ...
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- 1540 Olentangy River Rd, Columbus, OH · Directions · (614) 299-2253