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Levonorgestrel is a hormonal medication which is used in a number of birth control methods. [3] [7] It is combined with an estrogen to make combination birth control pills. [8]As an emergency birth control, sold under the brand names Plan B One-Step and Julie, among others, it is useful within 72 hours of unprotected sex.
A levonorgestrel-releasing implant was approved for medical use in 1983 in Finland and in the United States in 1990. [1] It is on the World Health Organization's List of Essential Medicines. [6] Levonorgestrel implants are approved in more than 60 countries and used by more than seven million women. [7] [8] As of 2015 it is approved but not ...
Researchers from the Danish Cancer Society Research Center have found an association between levonorgestrel-releasing intrauterine systems (LNG-IUSs) and increased breast cancer risk in females ...
In a 10-year study, the levonorgestrel coil was found to be as effective as oral medicines (tranexamic acid, mefenamic acid, combined oestrogen–progestogen or progesterone alone) for heavy periods; the same proportion of women had not had surgery for heavy bleeding and had similar improvements in their quality of life.
Other common side effects (each reported by less than 20% of levonorgestrel-only users in both the 1998 and 2002 WHO trials) were abdominal pain, fatigue, headache, dizziness, and breast tenderness. [ 25 ] [ 28 ] [ 33 ] [ 36 ] Side effects generally resolve within 24 hours, [ 13 ] although temporary disruption of the menstrual cycle is commonly ...
A 2012 meta-analysis estimated that the absolute risk of VTE is 2 per 10,000 women for non-use, 8 per 10,000 women for ethinylestradiol and levonorgestrel-containing birth control pills, and 10 to 15 per 10,000 women for birth control pills containing ethinylestradiol and a newer-generation progestin. [76]
Users of levonorgestrel often experience menses before the expected date. [40] A prescription for levonorgestrel is not needed and can be found over the counter at local pharmacies. [45] Because levonorgestrel does not have any life-threatening side effects, it has been approved by the FDA for use by all age groups. [45]
Side effects of the combination of an estrogen and norgestimate include menstrual irregularities, headaches, nausea, abdominal pain, breast tenderness, mood changes, and others. [ 3 ] [ 4 ] Norgestimate is a progestin, or a synthetic progestogen , and hence is an agonist of the progesterone receptor , the biological target of progestogens like ...
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