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Mucus is released in the stomach and intestine, and serves to lubricate and protect the inner mucosa of the tract. It is composed of a specific family of glycoproteins termed mucins and is generally very viscous. Mucus is made by two types of specialized cells termed mucous cells in the stomach and goblet cells in the intestines. Signals for ...
Goblet cells are simple columnar epithelial cells, having a height of four times that of their width. The cytoplasm of goblet cells tends to be displaced toward the basal end of the cell body by the large mucin granules, which accumulate near the apical surface of the cell along the Golgi apparatus, which lies between the granules and the nucleus.
Foveolar cells line the surface of the stomach and the gastric pits. They constitute a simple columnar epithelium, as they form a single layer of cells and are taller than their width. Other mucus-secreting cells are the mucous neck cells in the necks of the gastric glands. [2]: 257
The cells in the respiratory epithelium are of five main types: a) ciliated cells, b) goblet cells, c) brush cells, d) airway basal cells, and e) small granule cells (NDES) [6] Goblet cells become increasingly fewer further down the respiratory tree until they are absent in the terminal bronchioles; club cells take over their role to some extent here. [7]
Mucus is made up of a fluid component of around 95% water, the mucin secretions from the goblet cells, and the submucosal glands (2–3% glycoproteins), proteoglycans (0.1–0.5%), lipids (0.3–0.5%), proteins, and DNA. [7] The major mucins secreted – MUC5AC and MUC5B - are large polymers that give the mucus its rheologic or viscoelastic ...
The ciliated part of the simple columnar epithelium has tiny hairs which help move mucus and other substances up the respiratory tract. The shape of the simple columnar epithelium cells are tall and narrow giving a column like appearance. the apical surfaces of the tissue face the lumen of organs while the basal side faces the basement membrane ...
The epithelium, the most exposed part of the mucosa, is a glandular epithelium with many goblet cells. Goblet cells secrete mucus , which lubricates the passage of food along and protects the intestinal wall from digestive enzymes.
Goblet cells secrete the mucus layer which protects the epithelium from the luminal contents. Enteroendocrine cells secrete various gastrointestinal hormones including secretin, pancreozymin, enteroglucagon among others. Subsets of sensory intestinal epithelial cells synapse with nerves, [9] and are known as neuropod cells. [10]