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13.1 The Practice of Medicinal Chemistry. 14 See also. ... Download as PDF; ... The most comprehensive one-volume text on inorganic chemistry available; ...
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use.
Pan-assay interference compounds (PAINS) are chemical compounds that often give false positive results in high-throughput screens. [1] PAINS tend to react nonspecifically with numerous biological targets rather than specifically affecting one desired target. [2] A number of disruptive functional groups are shared by many PAINS. [2] [3] [4]
ChemMedChem is a biweekly peer-reviewed scientific journal covering medicinal chemistry.It is published by Wiley-VCH on behalf of Chemistry Europe.In addition to original research in the form of full papers and shorter communications, the journal contains review-type articles (reviews, minireviews, patent reviews, essays, highlights) as well as occasional book reviews and conference reports.
ACS Medicinal Chemistry Letters is a monthly peer-reviewed scientific journal covering medicinal chemistry. It was established in 2009 and is published by the American Chemical Society. The editor-in-chief is Dennis C. Liotta (Emory University). According to the Journal Citation Reports, the journal has a 2021 impact factor of 4.632. [1]
Alfred Burger (6 September 1905 – 30 December 2000) was a prominent chemist and a pioneer in medical chemistry. Burger was born in Vienna, the capitol of the Austro-Hungarian Empire, on 6 September 1905. [2]
Based on one definition, a drug-like molecule has a logarithm of partition coefficient (log P) between −0.4 and 5.6, molecular weight 160–480 g/mol, molar refractivity of 40–130, which is related to the volume and molecular weight of the molecule and has 20–70 atoms.
Medicinal Chemistry Research is a peer-reviewed scientific journal of medicinal chemistry emphasizing the structure-activity relationships of biologically active compounds. [1] It was founded in 1991 by Alfred Burger (University of Virginia), who also founded the Journal of Medicinal Chemistry. [2] The journal is currently edited by Longqin Hu.
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