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Activator protein 1 (AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and bacterial and viral infections. [1] AP-1 controls a number of cellular processes including differentiation, proliferation, and apoptosis. [2]
A transcriptional activator is a protein (transcription factor) that increases transcription of a gene or set of genes. [1] Activators are considered to have positive control over gene expression, as they function to promote gene transcription and, in some cases, are required for the transcription of genes to occur.
AP1 or AP-1 may refer to: Biology. Activator protein 1, dimeric transcription factor; Adaptor protein 1, tetrameric clathrin-associated complex; Transportation
It consists of 267 amino acids. The cDNA of MMP7 is 49% homologous to stromelysin-1. [12] Comparing to other members of MMP family, MMP7 does not have a C-terminal protein domain. [14] The promoter of the human MMP7 contains a TATA box, an activator protein 1 (AP-1) site, and two inverted polyomavirus enhancer A-binding proteins 2 (PEA-3).
It has been mapped to chromosome region 14q21→q31. c-Fos encodes a 62 kDa protein, which forms heterodimer with c-jun (part of Jun family of transcription factors), resulting in the formation of AP-1 (Activator Protein-1) complex which binds DNA at AP-1 specific sites at the promoter and enhancer regions of target genes and converts ...
Three employees at a Maryland Cracker Barrel have reportedly been dismissed after staff refused to seat a group of students with special needs on Dec. 3 Superintendent of Charles County Public ...
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However, Dr. Kobylarz notes it can start as early as 1 p.m. for some people. What Sundowning Looks Like There’s a difference between being totally over your day and sundowning.