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  2. List of antineoplastic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_antineoplastic_agents

    Tyrosine kinase inhibitor (TKI) with selective activity against RET, VEGFR-2 and EGFR: Medullary thyroid cancer. Diarrhoea, hypertension, QT interval prolongation, depression, electrolyte anomalies, hypothyroidism and GI perforation (uncommon). 2.3 mTOR inhibitors: Everolimus: PO: mTOR inhibitor.

  3. Category:Kinase inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:Kinase_inhibitors

    Download as PDF; Printable version; In other projects Wikimedia Commons; Wikidata item; ... Protein kinase inhibitors (4 C, 62 P) Pages in category "Kinase inhibitors"

  4. Category:Tyrosine kinase inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:Tyrosine_kinase...

    Download as PDF; Printable version; In other projects ... move to sidebar hide. Help. Inhibitors of tyrosine kinase are mainly used against some specific forms of ...

  5. Category:Receptor tyrosine kinase inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:Receptor_tyrosine...

    Download as PDF; Printable version; ... Pages in category "Receptor tyrosine kinase inhibitors" ... out of 41 total. This list may not reflect recent changes. A.

  6. Tyrosine kinase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Tyrosine_kinase_inhibitor

    Adavosertib is a Wee1 kinase inhibitor that is undergoing numerous clinical trials in the treatment of refractory solid tumors. [9] However, toxicities such as myelosuppression , diarrhea , and supraventricular tachyarrhythmia have arisen while attempting to determine the toxicity and effectiveness of the drug.

  7. Protein kinase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Protein_kinase_inhibitor

    A protein kinase inhibitor (PKI) is a type of enzyme inhibitor that blocks the action of one or more protein kinases. Protein kinases are enzymes that phosphorylate (add a phosphate , or PO 4 , group) to a protein and can modulate its function.

  8. Category:Protein kinase inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:Protein_kinase...

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  9. Rho kinase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Rho_kinase_inhibitor

    A number of Rho kinase inhibitors are known. [15] [16] [17]Chemical structure of fasudil. AT-13148 [18]; BA-210; β-ElemeneBelumosudil; Chroman 1 [19] [20]; DJ4, which is a selective multi-specific ATP competitive inhibitor of activity of ROCK1 (IC50 of 5 nM), ROCK2 (IC50 of 50 nM), MRCKα (IC50 of 10 nM) and MRCKβ (IC50 of 100 nM) kinases without affecting activity of PAK1 and DMPK at 5 μM ...