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Amphetamine type stimulants can be used in the treatment of narcolepsy, a rare neurological disorder where the brain is unable to regulate the sleep-wake mechanism. [17] Amphetamines causes an increase in dopamine release, which is the proposed mechanism for its wake-promoting effect. [18]
Methamphetamine is excreted by the kidneys, with the rate of excretion into the urine heavily influenced by urinary pH. [25] [144] When taken orally, 30–54% of the dose is excreted in urine as methamphetamine and 10–23% as amphetamine. [144] Following IV doses, about 45% is excreted as methamphetamine and 7% as amphetamine. [144]
The adverse side effects of amphetamine are many and varied, and the amount of amphetamine used is the primary factor in determining the likelihood and severity of adverse effects. [28] [40] Amphetamine products such as Adderall, Dexedrine, and their generic equivalents are currently approved by the U.S. FDA for long-term therapeutic use.
A history of the drug crystal meth. For premium support please call: 800-290-4726 more ways to reach us
MDA is a substituted methylenedioxylated phenethylamine and amphetamine derivative. In relation to other phenethylamines and amphetamines, it is the 3,4-methylenedioxy, α-methyl derivative of β-phenylethylamine, the 3,4-methylenedioxy derivative of amphetamine, and the N-desmethyl derivative of MDMA.
3-Methylamphetamine (3-MeA; PAL-314) is a stimulant drug from the amphetamine family. It is self-administered by mice to a similar extent to 4-fluoroamphetamine and has comparable properties as a monoamine releaser, [1] although with a more balanced release of all three monoamines, as opposed to the more dopamine/noradrenaline selective fluoro analogues.
Dimethylamphetamine has weaker stimulant effects than amphetamine or methamphetamine and is considerably less addictive [1] and less neurotoxic compared to methamphetamine. [2] [3] However, it still retains some mild stimulant effects and abuse potential, [4] and is a Schedule I controlled drug.
Crystal methamphetamine (most commonly, colloquially known as "crystal meth" or "ice") and free base forms of amphetamine are sufficiently volatile substances and this allows them to be vaporized by high heat (i.e. using a lighter) and the fumes are inhaled (or "smoked") from glass paraphernalia known as base pipes (most commonly, colloquially ...