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The SOLiD Sequencing System uses probes with dual base encoding. The underlying chemistry is summarized in the following steps: [12] - Step 1, Preparing a Library: This step begins with shearing the genomic DNA into small fragments. Then, two different adapters are added (for example A1 and A2).
It uses 2 base encoding to decode the raw data generated by the sequencing platform into sequence data. This method should not be confused with "sequencing by synthesis," a principle used by Roche-454 pyrosequencing (introduced in 2005, generating millions of 200-400bp reads in 2009), and the Solexa system (now owned by Illumina) (introduced in ...
As an example, the ground state configuration of the sodium atom is 1s 2 2s 2 2p 6 3s 1, as deduced from the Aufbau principle (see below). The first excited state is obtained by promoting a 3s electron to the 3p subshell, to obtain the 1s 2 2s 2 2p 6 3p 1 configuration, abbreviated as the 3p level. Atoms can move from one configuration to ...
Fig. 2 DNA-encoded library by ‘DNA-templated synthesis’A library of oligonucleotides (i.e. 64 different oligonucleotides) containing three coding regions was hybridized to a library of reagent compound-oligonucleotide conjugates (i.e. 4 reagent oligonucleotide conjugates), able of pairing with the initial coding domain of the template ...
The International Chemical Identifier (InChI, pronounced / ˈ ɪ n tʃ iː / IN-chee) [3] is a textual identifier for chemical substances, designed to provide a standard way to encode molecular information and to facilitate the search for such information in databases and on the web.
Packetized Elementary Stream (PES) is a specification in the MPEG-2 Part 1 (Systems) (ISO/IEC 13818-1) and ITU-T H.222.0 [1] [2] that defines carrying of elementary streams (usually the output of an audio or video encoder) in packets within MPEG program streams and MPEG transport streams. [3]
(1,7) RLL maps 2 bits of data onto 3 bits on the disk, and the encoding is done in 2- or 4-bit groups. The encoding rules are: (x, y) becomes (NOT x, x AND y, NOT y), except (x, 0, 0, y) becomes (NOT x, x AND y, NOT y, 0, 0, 0). [7] When encoding according to the table below, the longest (last in the table) match must be used; those are ...
A character encoding form (CEF) is the mapping of code points to code units to facilitate storage in a system that represents numbers as bit sequences of fixed length (i.e. practically any computer system). For example, a system that stores numeric information in 16-bit units can only directly represent code points 0 to 65,535 in each unit, but ...