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  2. Esketamine - Wikipedia

    en.wikipedia.org/wiki/Esketamine

    Esketamine is the second drug to be approved for TRD by the FDA, following olanzapine/fluoxetine (Symbyax) in 2009. [25] [50] Other agents, like the atypical antipsychotics aripiprazole (Abilify) and quetiapine (Seroquel), have been approved for use in the adjunctive therapy of MDD in people with a partial response to treatment. [25]

  3. Ketamine-assisted psychotherapy - Wikipedia

    en.wikipedia.org/wiki/Ketamine-assisted...

    In 2019, the FDA approved the use of esketamine (Spravato) as a nasal spray, in conjunction with an oral antidepressant, for treatment-resistant depression in adults. Potential risks associated with it include dissociation, sedation and abuse. Esketamine cannot be distributed outside of certified clinical settings. [11]

  4. Ketamine in society and culture - Wikipedia

    en.wikipedia.org/wiki/Ketamine_in_society_and...

    After the publication of the NIH-run antidepressant clinical trial, clinics began opening in which the intravenous ketamine is given for depression. [5] [6] This practice is an off label use of IV ketamine in the United States, though the intranasal version of esketamine has been approved by the FDA for treatment of depression [5] [7] In 2015 there were about 60 such clinics in the US; the ...

  5. FDA Approves Major Novel Depression Drug For First Time ... - AOL

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  6. What You Need to Know About Esketamine, the First Nasal ... - AOL

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  7. Velpatasvir - Wikipedia

    en.wikipedia.org/wiki/Velpatasvir

    Velpatasvir reaches highest blood plasma levels three hours after oral intake together with sofosbuvir. Plasma protein binding is over 99.5%. It is slowly metabolised by the liver enzymes CYP2B6, CYP2C8 and CYP3A4.

  8. Liquidia's inhaled drug fails to get traditional approval in ...

    www.aol.com/news/us-fda-grants-tentative...

    (Reuters) -The U.S. Food and Drug Administration on Monday delayed traditional approval for Liquidia Corp's inhaled drug for types of lung disorders, and allowed only tentative clearances, sending ...

  9. Sofosbuvir/velpatasvir - Wikipedia

    en.wikipedia.org/wiki/Sofosbuvir/velpatasvir

    Sofosbuvir/velpatasvir, sold under the brand name Epclusa among others, is a fixed-dose combination medication for the treatment of hepatitis C in adults. [ 2 ] [ 5 ] [ 6 ] [ 7 ] It combines sofosbuvir and velpatasvir .