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For others, it reduces alcohol consumption and the cravings that trigger binge use or relapses. Naltrexone is one of three standard FDA-approved medications currently on the market to treat AUD.
Acamprosate, sold under the brand name Campral, is a medication which reduces alcoholism cravings. [ 1 ] [ 5 ] It is thought to stabilize chemical signaling in the brain that would otherwise be disrupted by alcohol withdrawal . [ 6 ]
These medications help reduce cravings and withdrawal symptoms, but we know that around half of patients who start medications for opioid use disorder stop taking them after six months.
Contrary to earlier beliefs, detoxification and alcohol deprivation did not stop alcohol craving but in fact increased subsequent alcohol drinking. [ 2 ] [ 3 ] After getting his doctorate in 1972 from the University of Oregon on the ADE, Sinclair immediately went to Helsinki to work at Alko Laboratories (now part of Finland's National Public ...
Then there is the question of whether the drug would stop working for alcohol cravings when people stop taking it, the way it does for weight loss.
Disulfiram is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase (specifically the ALDH2 enzyme [3]), causing many of the effects of a hangover to be felt immediately following alcohol consumption.
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