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Novolin is the brand name of three distinct insulin-containing products [1] manufactured by Novo Nordisk: [2] Novolin 70/30, an insulin preparation containing mixed NPH and regular insulin, respectively; Novolin N, an insulin preparation containing NPH insulin; Novolin R, an insulin preparation containing regular insulin
NPH insulin is cloudy and has an onset of 1–3 hours. Its peak is 6–8 hours and its duration is up to 24 hours. [9]It has an intermediate duration of action, meaning longer than that of regular and rapid-acting insulin, and shorter than long acting insulins (ultralente, glargine or detemir).
NovoLog Mix 70/30 is a product which contains 30% insulin aspart and 70% insulin aspart protamine. [14] The insulin aspart protamine portion is a crystalline form of insulin aspart, which delays the action of the insulin, giving it a prolonged absorption profile after injection. [14]
The combination products begin to work with the shorter-acting insulin (5–15 minutes for fast-acting, and 30 minutes for short-acting), and remain active for 16–24 hours. There are several variations with different proportions of the mixed insulins (e.g. Novolog Mix 70/30 contains 70% aspart protamine [akin to NPH], and 30% aspart.) [49]
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70/30 may refer to: 70/30 Productions; A form of insulin therapy, consisting of 70% intermediate-acting, and 30% fast-acting insulin.
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