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2. Nortriptyline - Wikipedia

   en.wikipedia.org/wiki/Nortriptyline

   Nortriptyline is an active metabolite of amitriptyline by demethylation in the liver. Chemically, it is a secondary amine dibenzocycloheptene and pharmacologically it is classed as a first-generation antidepressant. [36] Nortriptyline may also have a sleep-improving effect due to antagonism of the H 1 and 5-HT 2A receptors. [37]

3. List of antidepressants - Wikipedia

   en.wikipedia.org/wiki/List_of_antidepressants

   Nortriptyline (Pamelor, Aventyl) Noxiptiline (Agedal, Elronon, Nogedal) Pipofezine (Azafen/Azaphen) Protriptyline (Vivactil) Trimipramine (Surmontil) Opipramol (Insidon), tianeptine (Stablon, Coaxil) and amineptine (discontinued; formerly Survector, Maneon) are chemically TCAs but are pharmacodynamically atypical, and are therefore grouped ...

4. Tricyclic antidepressant - Wikipedia

   en.wikipedia.org/wiki/Tricyclic_antidepressant

   A 2024 systematic review and meta-analysis assessed the beneficial and harmful effects of TCAs in the treatment of major depressive disorder in adults. [11] Previous systematic reviews and meta-analyses had not comprehensively assessed TCAs in the same fashion, with the largest including only two TCAs ( amitriptyline and clomipramine ) and only ...

5. This 2-hour window is the best time of day to work out for ...

   www.aol.com/news/best-time-day-200734418.html

   When it comes to weight loss, a 2023 study published in the journal Obesity found exercising between 7 a.m. and 9 a.m. could help. Based on data from 5,200 people 20 years old and over ...

6. Amitriptyline - Wikipedia

   en.wikipedia.org/wiki/Amitriptyline

   Nortriptyline reaches 10% higher level in the blood plasma than the parent drug amitriptyline and 40% greater area under the curve, and its action is an important part of the overall action of amitriptyline. [5] [9] Another active metabolite is (E)-10-hydroxynortriptyline, which is a norepinephrine uptake inhibitor four times weaker than ...

7. Second-generation antidepressant - Wikipedia

   en.wikipedia.org/wiki/Second-generation...

   The second-generation antidepressants are a class of antidepressants characterized primarily by the era of their introduction, approximately coinciding with the 1970s and 1980s, rather than by their chemical structure or by their pharmacological effect.