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Dextromethorphan, sold under the brand name Robitussin among others, is a cough suppressant used in many cough and cold medicines. [6] In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in people with major depressive disorder .
As a cough suppressant, the polistirex version lasts up to 12 hours. This duration also holds true when used recreationally. In 1981, a paper by Gosselin estimated that the lethal dose is between 50 and 500 mg/kg. Doses as high as 15–20 mg/kg are taken by some recreational users.
Dextromethorphan is a cough suppressant found in several cold medications. Several U.S. states have begun regulating who, and under what circumstances, can purchase dextromethorphan containing products. Not all states have regulations documented at this time, but this article contains all the states that have documentation.
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Robitussin Honey CF Max NT Adult 8oz Lots: T08740 (June 30, 2026), T08742 (June 30, 2026) The elderly and very young people are most likely to experience complications from fungemia.
Robitussin cough syrup is being recalled due to microbial contamination that can lead to fungemia. Honey flavors are included in the 2024 recall.
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