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Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease, also known as pseudogout and pyrophosphate arthropathy, is a rheumatologic disease which is thought to be secondary to abnormal accumulation of calcium pyrophosphate dihydrate crystals within joint soft tissues. [1]
Symptoms can start within an hour of exposure, and can last for several months. [1] [3] [5] Early symptoms are usually nausea, vomiting and loss of appetite. [1] In the following hours or weeks, initial symptoms may appear to improve, before the development of additional symptoms, after which either recovery or death follow. [1]
A magnesium deficiency may cause chondrocalcinosis, and there is anecdotal evidence that magnesium supplementation may reduce or alleviate symptoms. [7] In some cases, arthritis from injury can cause chondrocalcinosis. [8] Other causes of chondrocalcinosis include: [4] Hypercalcaemia, especially when caused by hyperparathyroidism; Arthritis ...
During a gout flare-up, you may experience symptoms that last a week or two, after which they typically go away. Many people with gout don’t have any symptoms between flares. Many people with ...
Currently, there is a lot of debate about what interventions are the most effective for parents, and often the efficacy of therapy appears to depend on the child's condition. For example, psychotherapy has helped improve parental adaptive behaviors in parents of children with cancer but not in others. [21]
Cancer in children is rare in the UK, with an average of 1,800 diagnoses every year but contributing to less than 1% of all cancer-related deaths. [70] Age is not a confounding factor in mortality from the disease in the UK. From 2014 to 2016, approximately 230 children died from cancer, with brain/CNS cancers being the most commonly fatal type.
Research shows that children with cancer are at risk for developing various cognitive or learning problems. These difficulties may be related to brain injury stemming from the cancer itself, such as a brain tumor or central nervous system metastasis or from side effects of cancer treatments such as chemotherapy and radiation therapy .
The most common cause of primary hyperparathyroidism is a sporadic, single parathyroid adenoma [5] resulting from a clonal mutation (~97%). Less common are parathyroid hyperplasia [6] (~2.5%), parathyroid carcinoma (malignant tumor), and adenomas in more than one gland (together ~0.5%).Primary hyperparathyroidism is also a feature of several familial endocrine disorders: Multiple endocrine ...