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  2. Motor neuron diseases - Wikipedia

    en.wikipedia.org/wiki/Motor_neuron_diseases

    Symptoms of motor neuron diseases can be first seen at birth or can come on slowly later in life. Most of these diseases worsen over time; while some, such as ALS, shorten one's life expectancy, others do not. [2] Currently, there are no approved treatments for the majority of motor neuron disorders, and care is mostly symptomatic. [2]

  3. Cancer survival rates - Wikipedia

    en.wikipedia.org/wiki/Cancer_survival_rates

    In males, researchers suggest that the overall reduction in cancer death rates is due in large part to a reduction in tobacco use over the last half century, estimating that the reduction in lung cancer caused by tobacco smoking accounts for about 40% of the overall reduction in cancer death rates in men and is responsible for preventing at least 146,000 lung cancer deaths in men during the ...

  4. Leptomeningeal cancer - Wikipedia

    en.wikipedia.org/wiki/Leptomeningeal_cancer

    Leptomeningeal cancer is a rare complication of cancer in which the disease spreads from the original tumor site to the meninges surrounding the brain and spinal cord. [1] This leads to an inflammatory response, hence the alternative names neoplastic meningitis (NM), malignant meningitis , or carcinomatous meningitis .

  5. Terminal illness - Wikipedia

    en.wikipedia.org/wiki/Terminal_illness

    What these patients often do give up, however, is quality of life at the end of life by undergoing intense and often uncomfortable treatment. A meta-analysis of 34 studies including 11,326 patients from 11 countries found that less than half of all terminal patients correctly understood their disease prognosis , or the course of their disease ...

  6. Spinal and bulbar muscular atrophy - Wikipedia

    en.wikipedia.org/wiki/Spinal_and_bulbar_muscular...

    Spinal and bulbar muscular atrophy (SBMA), popularly known as Kennedy's disease, is a rare, adult-onset, X-linked recessive lower motor neuron disease caused by trinucleotide CAG repeat expansions in exon 1 of the androgen receptor (AR) gene, which results in both loss of AR function and toxic gain of function.

  7. Overdiagnosis - Wikipedia

    en.wikipedia.org/wiki/Overdiagnosis

    There are various cancer types for which a standard contraindication to screening is life expectancy of less than 10 years, for the simple and logical reason that a person who already has medically complex health status (e.g., multiple comorbidities) and realistically can probably expect to live for less than 10 years is less likely to get a ...

  8. Five-year survival rate - Wikipedia

    en.wikipedia.org/wiki/Five-year_survival_rate

    Five-year survival rates can be used to compare the effectiveness of treatments. Use of five-year survival statistics is more useful in aggressive diseases that have a shorter life expectancy following diagnosis, such as lung cancer, and less useful in cases with a long life expectancy, such as prostate cancer.

  9. Neurofibromatosis - Wikipedia

    en.wikipedia.org/wiki/Neurofibromatosis

    There is no known prevention or cure. [1] [2] Surgery may be done to remove tumors that are causing problems or have become cancerous. [1] Radiation and chemotherapy may also be used if cancer occurs. [1] A cochlear implant or auditory brainstem implant may help some who have hearing loss due to the condition. [1]