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Mesotrione is a selective herbicide used mainly in maize crops. [1] It is a synthetic compound inspired by the natural substance leptospermone found in the bottlebrush tree Callistemon citrinus . It inhibits the enzyme 4-hydroxyphenylpyruvate dioxygenase (HPPD) [ 3 ] and is sold under brand names including Callisto and Tenacity.
Peripheral neuropathy and mononeuropathy are common neurological disorders, with a diverse range of variables and causes to conclude a diagnosis. [2] Neuropathy has three sub-classifications; mononeuropathy is a result of an entrapped or traumatised nerve or nerve area, Mononeuropathy multiplex is linked to chronic diseases like leprosy, and ...
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
The use of gene therapy is a potential treatment for chronic neuropathic pain. [54] In animals a gene therapy for local transgenes encoding for GABA synthesizing-releasing inhibitory machinery has been demonstrated and was effective for months at a time.
Non-cytotoxic immunosuppressive treatments usually include the anti-rejection transplant drugs azathioprine (Imuran/Azoran) and mycophenolate mofetil (Cellcept). In the U.S., these drugs are used "off-label", meaning that they do not have an indication for the treatment of CIDP in their package inserts.
Neuritis (/ nj ʊəˈr aɪ t ɪ s /), from the Greek νεῦρον), [1] is inflammation of a nerve [2] or the general inflammation of the peripheral nervous system.Inflammation, and frequently concomitant demyelination, [3] [4] [5] cause impaired transmission of neural signals and leads to aberrant nerve function.
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