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Bcl-2 homologous antagonist/killer is a protein which in humans is encoded by the BAK1 gene on chromosome 6. [4] [5] It belongs to the BCL2 protein family.BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.
Apoptosis regulator BAX, also known as bcl-2-like protein 4, is a protein that in humans is encoded by the BAX gene. [5] BAX is a member of the Bcl-2 gene family.BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.
Bax/Bak are believed to initiate apoptosis by forming a pore in the mitochondrial outer membrane that allows cytochrome c to escape into the cytoplasm and activate the pro-apoptotic caspase cascade. The anti-apoptotic Bcl-2 and Bcl-xL proteins inhibit cytochrome c release through the mitochondrial pore and also inhibit activation of the ...
The p53 upregulated modulator of apoptosis (PUMA) also known as Bcl-2-binding component 3 (BBC3), is a pro-apoptotic protein, member of the Bcl-2 protein family. [5] [6] In humans, the Bcl-2-binding component 3 protein is encoded by the BBC3 gene.
Benzalkonium chloride (BZK, BKC, BAK, BAC), also known as alkyldimethylbenzylammonium chloride (ADBAC) and by the trade name Zephiran, [1] is a type of cationic surfactant. It is an organic salt classified as a quaternary ammonium compound. ADBACs have three main categories of use: as a biocide, a cationic surfactant, and a phase transfer agent ...
Initiation of MOMP involves Bcl-2 family proteins, including BAX and BAK. [1] The outer mitochondrial membrane, typically permeable to molecules smaller than 5 kDa, forms pores during MOMP that allow it to accommodate proteins larger than 100 kDa. During MOMP, it takes about five minutes for all mitochondrial membranes within a cell to ...
Kristian Bach Bak (né Bak Nielsen; born 20 October 1982) is a Danish former professional footballer. Bak usually played centre-back , but he has a past as a striker . He has played one game for the Danish under-21 national team .
During the 2018 EU LCS Season, Caps managed to win both the Spring and Summer Split with his then team, Fnatic.In both splits, he secured a spot on the 1st All-Pro Team. Additionally, he managed to win the title of most valuable player (MVP) in the Summer Spl