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Pentane-2,4-dione (keto form) Other names ... Hacac; 2,4-Pentanedione; Identifiers CAS Number. 123-54-6 ... In some cases the chelate effect is so strong that no ...
Pentanedione may refer to: Acetylacetone (2,4-pentanedione) Acetylpropionyl (2,3-pentanedione) See also. C 5 H 8 O 2; Cyclopentanedione
The mechanism of action is a crucial factor in determining effect and toxicity of the drug, taking in consideration the pharmacokinetic (PK) factors. [12] The sort and extent of altered cellular physiology will depend on the combination of the drug's presence (as established by pharmacokinetic (PK) studies) and/or its mechanism and duration of ...
Pharmacokinetics: . Process of the uptake of drugs by the body, the biotransformation they undergo, the distribution of the drugs and their metabolites in the tissues, and the elimination of the drugs and their metabolites from the body over a period of time.
In organic chemistry, steric effects are nearly universal and affect the rates and activation energies of most chemical reactions to varying degrees. In biochemistry, steric effects are often exploited in naturally occurring molecules such as enzymes , where the catalytic site may be buried within a large protein structure.
The alpha effect refers to the increased nucleophilicity of an atom due to the presence of an adjacent (alpha) atom with lone pair electrons. [2] This first atom does not necessarily exhibit increased basicity compared with a similar atom without an adjacent electron-donating atom, resulting in a deviation from the classical Brønsted-type ...
The oligodynamic effect (from Greek oligos, "few", and dynamis, "force") is a biocidal effect of metals, especially heavy metals, that occurs even in low concentrations. This effect is attributed to the antibacterial behavior of metal ions, which are absorbed by bacteria upon contact and damage their cell membranes .
However, another effect that plays a role is the +M effect which adds electron density back into the benzene ring (thus having the opposite effect of the -I effect but by a different mechanism). This is called the mesomeric effect (hence +M) and the result for fluorine is that the +M effect approximately cancels out the -I effect.