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Fasedienol (INN Tooltip International Nonproprietary Name; developmental code names PH94B and Aloradine), also known as 4-androstadienol or as 4,16-androstadien-3β-ol, is a pherine which is under development by VistaGen Therapeutics [1] [2] in a nasal spray formulation for the acute treatment of social anxiety disorder.
A Phase 0 study gives no data on safety or efficacy, being by definition a dose too low to cause any therapeutic effect. Drug development companies carry out Phase 0 studies to rank drug candidates to decide which has the best pharmacokinetic parameters in humans to take forward into further development. They enable go/no-go decisions to be ...
Accurate computer models of a treatment and its deployment, as well as patient characteristics, are necessary precursors for the development of in silico clinical trials. [5] [6] [8] [9] In such a scenario, ‘virtual’ patients would be given a ‘virtual’ treatment, enabling observation through a computer simulation of how the candidate biomedical product performs and whether it produces ...
The Phase 3 KOASTAL-2, KOASTAL-3, and KOASTAL-LT studies are ongoing. Price Action: At last check Thursday, NMRA stock was down 83.6% to $1.74 during the premarket session. Read Next:
Phase II clinical trials for multiple myeloma and myelofibrosis reported 'promising results'. [ 22 ] [ 23 ] Phase III results showed significant extension of progression-free survival , and overall survival (median 11.9 months vs. 7.8 months; p = 0.0002) in patients taking pomalidomide and dexamethasone vs. dexamethasone alone.
This second patch of freedom lasted a little over a year, maybe two or three months longer than my first cancer-free period. During that time, my sister and I moved to Southern California to be ...
However, in the Phase 3 TH-CR-406/SARC021 study (conducted in collaboration with the Sarcoma Alliance for Research through Collaboration (SARC)), patients with locally advanced unresectable or metastatic soft tissue sarcoma treated with evofosfamide in combination with doxorubicin did not demonstrate a statistically significant improvement in ...
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