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Infant respiratory distress syndrome (IRDS), also known as surfactant deficiency disorder (SDD), [2] and previously called hyaline membrane disease (HMD), is a syndrome in premature infants caused by developmental insufficiency of pulmonary surfactant production and structural immaturity in the lungs.
Causes may include sepsis, pancreatitis, trauma, pneumonia, and aspiration. [1] The underlying mechanism involves diffuse injury to cells which form the barrier of the microscopic air sacs of the lungs , surfactant dysfunction, activation of the immune system , and dysfunction of the body's regulation of blood clotting . [ 5 ]
The most immediate injury caused by asphyxia is hypoxia, which can in turn cause acute lung injury or acute respiratory distress syndrome as well as damage to the circulatory system. The most severe injury associated with asphyxiation is cerebral hypoxia and ischemia , in which the brain receives insufficient oxygen or blood, resulting in ...
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Salmonella, a type of bacteria, is a leading cause of foodborne illness, hospitalizations and deaths in the U.S., according to the Centers for Disease Control and Prevention.
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The causes listed are relatively immediate medical causes, but the ultimate cause of death might be described differently. For example, tobacco smoking often causes lung disease or cancer, and alcohol use disorder can cause liver failure or a motor vehicle accident. For statistics on preventable ultimate causes, see preventable causes of death.
Oxygen toxicity is caused by hyperoxia, exposure to oxygen at partial pressures greater than those to which the body is normally exposed. This occurs in three principal settings: underwater diving, [ 34 ] hyperbaric oxygen therapy, [ 35 ] and the provision of supplemental oxygen, in critical care, [ 36 ] and for long-term treatment of chronic ...