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Intubation granuloma is a benign growth of granulation tissue in the larynx or trachea, which arises from tissue trauma due to endotracheal intubation. [1] This medical condition is described as a common late complication of tracheal intubation, specifically caused by irritation to the mucosal tissue of the airway during insertion or removal of the patient's intubation tube.
Examples of this use of the term granuloma are the lesions known as vocal cord granuloma (known as contact granuloma), pyogenic granuloma, and intubation granuloma, all of which are examples of granulation tissue, not granulomas. "Pulmonary hyalinizing granuloma" is a lesion characterized by keloid-like fibrosis in the lung and is not ...
Contact granuloma may also arise after intubation, and so following intubation, patients should be monitored if voice symptoms arise. Symptoms may or may not include hoarse voice , described as "huskiness" by some patients, [ 5 ] "aching" in the throat related to increased effort to produce voice, [ 5 ] and the feeling of having a lump in one's ...
It usually includes the formation of a foreign body granuloma. [2] Tissue encapsulation of an implant is an example, as is inflammation around a splinter . [ 3 ] Foreign body granuloma formation consists of protein adsorption , macrophages , multinucleated foreign body giant cells (macrophage fusion), fibroblasts , and angiogenesis .
Granulation tissue is composed of tissue matrix supporting a variety of cell types, [3] most of which can be associated with one of the following functions: formation of extracellular matrix;
The disease is still sometimes confused with lethal midline granuloma and lymphomatoid granulomatosis, both malignant lymphomas. [ 34 ] The full clinical picture was first presented by Friedrich Wegener (1907–1990), a German pathologist , in two reports in 1936 and 1939, leading to the eponymous name Wegener's granulomatosis or Wegener ...
Granuloma in the vocal cords is also a possible complication, which may cause a soft and whispery voice. The granuloma should eventually be coughed out, or in some case be removed manually. [ 18 ] Dysphonia is another common symptom in the first two months of recovery, but the issue gradually resolves in most patients.
Tracheal intubation, usually simply referred to as intubation, is the placement of a flexible plastic tube into the trachea (windpipe) to maintain an open airway or to serve as a conduit through which to administer certain drugs.