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High levels of LDL, cholesterol, or triglycerides can cause peripheral artery disease, in which the arteries that carry blood to your legs can narrow or become blocked.
Hyperlipidemia is abnormally high levels of any or all lipids (e.g. fats, triglycerides, cholesterol, phospholipids) or lipoproteins in the blood. [2] The term hyperlipidemia refers to the laboratory finding itself and is also used as an umbrella term covering any of various acquired or genetic disorders that result in that finding. [3]
Hypercholesterolemia, also called high cholesterol, is the presence of high levels of cholesterol in the blood. [1] It is a form of hyperlipidemia (high levels of lipids in the blood), hyperlipoproteinemia (high levels of lipoproteins in the blood), and dyslipidemia (any abnormalities of lipid and lipoprotein levels in the blood).
In addition to plaque formation, LDL-C molecules can undergo oxidation. [1] Oxidation can cause further accumulation of cholesterol and the release of inflammatory cytokines, which damages the blood vessels. [1] [7] Due to the damaging effects of LDL-C, high levels increase the risk for cardiovascular disease and indicate dyslipidemia. [1]
Low-density lipoprotein, known as LDL, is a complex structure with several components that allow cholesterol to circulate in the bloodstream, a watery environment.
According to a solid collection of scientific evidence, high levels of lipoprotein(a)—also known as Lp(a), pronounced “L-P-little-a”—leads to an increased risk of atherosclerotic ...
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