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Deuruxolitinib, sold under the brand name Leqselvi, is a medication used for the treatment of alopecia areata. [1] It is a Janus kinase inhibitor selective for JAK1 and JAK2 . [ 2 ] Although the relative effectiveness of deuruxolitinib and another Janus kinase inhibitor— baricitinib —for alopecia areata may vary depending on the population ...
Ivarmacitinib (SHR0302) is a small molecule drug and selective janus kinase 1 (JAK1) inhibitor. It is being developed for ulcerative colitis , [ 1 ] eczema , alopecia areata , and graft-versus-host disease .
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Rosemary Oil. A very common oil included in natural hair growth products, studies have noted the efficacy of rosemary in promoting hair growth. In one study, results showed that rosemary oil may ...
Ritlecitinib is a kinase inhibitor which inhibits Janus kinase 3 and tyrosine kinase. [ 6 ] [ 9 ] [ 10 ] The most common side effects include headache, diarrhea, acne, rashes, eczema, fever, mouth ulcers, dizziness, shingles rash, and abnormal findings in some laboratory test results.
Baricitinib is a Janus kinase (JAK) inhibitor that reversibly inhibits Janus kinase 1 with a half maximal inhibitory concentration (IC 50) of 5.9 nM and Janus kinase 2 with an IC 50 of 5.7 nM. Tyrosine kinase 2 , which belongs to the same enzyme family, is affected less (IC 50 = 53 nM), and Janus kinase 3 far less (IC 50 > 400 nM).
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