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The ciliospinal reflex (pupillary-skin reflex) consists of dilation of the ipsilateral pupil in response to pain applied to the neck, face, and upper trunk. If the right side of the neck is subjected to a painful stimulus, the right pupil dilates (increases in size 1-2mm from baseline).
loss of ciliospinal reflex; bloodshot conjunctiva, depending on the site of lesion. unilateral straight hair (in congenital Horner's syndrome); the hair on the affected side may be straight in some cases. heterochromia iridum (in congenital Horner's syndrome) [4] Interruption of sympathetic pathways leads to several implications.
The ciliospinal center (also known as Budge's center [1]) is a cluster of [citation needed] pre-ganglionic sympathetic neuron cell bodies located in the intermediolateral cell column (of the cornu laterale) at spinal cord segment (C8: Anatomic variation) T1-T2 [2]
Trigeminal fibers (Cranial nerve 5) relay in ciliary ganglion and carry sympathetic supply (yellow) Long ciliary nerve fibers (from the ophthalmic branch of CN 5) are the afferent limb of the blink reflex carrying sensory information from the cornea. Sphincter pupillae (circular fibers) and Dilator pupillae (radial fibers) muscles of the pupil.
The SCG receives pre-ganglionic sympathetic afferents from the ciliospinal center which synapse in the ganglion. Post-ganglionic efferents then leave the SCG and join the internal carotid nerve plexus of the internal carotid artery, accompanying first this artery and subsequently its branches to reach the orbit and ultimately innervate the dilator pupillae muscle to mediate pupillary dilatation.
The short ciliary nerves contain both parasympathetic and sympathetic nerve fibers. The parasympathetic fibers arise from the Edinger-Westphal nucleus and synapse in the ciliary ganglion via the oculomotor nerve, the postganglionic parasympathetics leave the ciliary ganglion in the short ciliary nerve and supply the ciliary body and iris.
The hypothalamospinal tract includes fibres by which the hypothalamus projects to the ciliospinal center in the spinal cord, a part of a brain circuit regulating pupillary dilatation as part of the pupillary reflex. [3] Some axons of the tract contain oxytocin. [1]
The sympathetic root originates from the internal carotid plexus with cell bodies in the superior cervical ganglion. The axons pass through the ganglion and enter the eye without synapsing into the short ciliary nerves. The sympathetic root contains the postganglionic sympathetic axons that provide sympathetic supply to the blood vessels of the ...