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Taurine (/ ˈ t ɔː r iː n /), or 2-aminoethanesulfonic acid, is a non-proteinogenic naturally occurring amino sulfonic acid that is widely distributed in animal tissues. [1] It is a major constituent of bile and can be found in the large intestine, and accounts for up to 0.1% of total human body weight.
CSAD plays a role in taurine production by decarboxylating CSA to hypotaurine. Taurine is the most abundant amino acid in mammals and plays roles as an antioxidant, membrane stabilizer and neurotransmitter or neuromodulator in the CNS [9] and recently has received growing attention as a biomarker for different diseases. [10]
Once secreted into the lumen of the intestine, bile salts are modified by gut bacteria. They are partially dehydroxylated. Their glycine and taurine groups are removed to give the secondary bile acids, deoxycholic acid and lithocholic acid. Cholic acid is converted into deoxycholic acid and chenodeoxycholic acid into lithocholic acid.
L-taurine (an amino acid) Prebiotics (fiber that feed good bacteria in your gut) ... There is some data to suggest that saffron, green tea, or turmeric can have a slight impact on GLP-1 production
Thus CDO is necessary for hypotaurine/taurine and sulfite/sulfate production. The role of CDO may vary between cell types as it can either be used primarily for taurine or sulfate production or for degradation of cysteine. [1] CDO reaction scheme showing cysteine sulfinic acid formation from cysteine by dioxygen incorporation
Generic structure of a taurate. R is an odd numbered alkyl group C n H 2n+1 with n = 7 – 17 carbon atoms.. Taurates (or taurides) are a group of mild anionic surfactants.They are composed of a hydrophilic head group, consisting of N-methyltaurine (2-methylaminoethanesulfonic acid) and a lipophilic residue, consisting of a long-chain carboxylic acid (fatty acid), both linked via an amide bond.
One of the main processes that occur in B. wadsworthia is hydrogen sulfide production, which is the product responsible for the bacterium's signature black dot. [6] B. wadsworthia is able to produce hydrogen sulfide through its taurine desulfonation pathway using isethionate sulfite-lyase (IslA). [6]
UDCA and its taurine conjugates comprise about 47% of the bile in American black bears and up to 76% in Asiatic bears. [1] [3] Ursodeoxycholic acid and tauroursodeoxycholic acid were first chemically synthesized in 1954 in Japan. [1] Ursodeoxycholic acid is produced in several countries for the treatment of gallstones and primary biliary ...
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