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The term variant of concern (VOC) for SARS-CoV-2, which causes COVID-19, is a category used for variants of the virus where mutations in their spike protein receptor binding domain (RBD) substantially increase binding affinity (e.g., N501Y) in RBD-hACE2 complex (genetic data), while also being linked to rapid spread in human populations ...
The timeline of the COVID-19 pandemic lists the articles containing the chronology and epidemiology of SARS-CoV-2, [1] the virus that causes the coronavirus disease 2019 and is responsible for the COVID-19 pandemic. The first human cases of COVID-19 occurred in Wuhan, People's Republic of China, on or about 17 November 2019. [2]
By March 5, more than 2,750 cases of COVID-19 variants were detected in 47 states; Washington, D.C.; and Puerto Rico. This number consisted of 2,672 cases of the B.1.1.7 variant, 68 cases of the B.1.351 variant, and 13 cases of the P.1 variant. [35]
FLiRT variants are subvariants of omicron and were responsible for most COVID-19 cases in the U.S. by the beginning of July 2024. The KP.1 and KP.2 strains of FLiRT are the dominant strains of the ...
The Omicron variant features as such for the first time in the overview of WHO's weekly operational update, namely "Supporting Omicron variant detection and COVID-19 response in southern Africa." As of 2 December, Botswana and South Africa have reported 19 and 172 Omicron variant cases, respectively, accounting for 62% of global cases.
February 2020. Feb. 10: Worldwide deaths from the 2019 Novel Coronavirus exceeded 1,000, topping the number killed by the 2002-2003 outbreak of SARS.
JN.1 is a COVID-19 variant that descended from BA.2.86, explains infectious disease expert Amesh Adalja, M.D., a senior scholar at the Johns Hopkins Center for Health Security. JN.1 is “another ...
Initial estimates of the basic reproduction number (R 0) for COVID-19 in January 2020 were between 1.4 and 2.5, [58] but a subsequent analysis claimed that it may be about 5.7 (with a 95 per cent confidence interval of 3.8 to 8.9). [59] In December 2021, the number of cases continued to climb due to several factors, including new COVID-19 variants.
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