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Bioactive glasses have been synthesized through methods such as conventional melting, quenching, the sol–gel process, flame synthesis, and microwave irradiation.The synthesis of bioglass has been reviewed by various groups, with sol-gel synthesis being one of the most frequently used methods for producing bioglass composites, particularly for tissue engineering applications.
Therefore, the apatite formation on the surface of biomaterials, soaked in the SBF solution, is considered a successful development of novel bioactive materials. [5] The SBF technique for surface modification of metallic implants is usually a time-consuming process, and obtaining uniform apatite layers on substrates takes at least 7 days, with ...
Bioactive metallic glass is a subset of bioactive glass, wherein the bulk material is composed of a metal-glass substrate and is coated with bioactive glass in order to make the material bioactive. The reasoning behind the introduction of the metallic base is to create a less brittle, stronger material that will be permanently implanted within ...
The formation of neocartilage can also be induced with bioactive glass by using an in vitro culture of chondrocyte-seeded hydrogels and can serve as a subchondral substrate for tissue-engineered osteochondral constructs. [1] The borate-based bioactive glass has controllable degradation rates in order to match the rate at which actual bone is ...
A bioactive compound is a compound that has an effect on a living organism, tissue or cell, usually demonstrated by basic research in vitro or in vivo in the laboratory. While dietary nutrients are essential to life, bioactive compounds have not been proved to be essential – as the body can function without them – or because their actions are obscured by nutrients fulfilling the function.
Bioactive glass S53P4 (BAG-S53P4) is a biomaterial consisting of sodium, silicate, calcium and phosphate. [1] S53P4 is osteoconductive and also osteoproductive in the promotion, migration, replication and differentiation of osteogenic cells and their matrix production. [ 2 ]
Bioactive ceramics, including bioglasses must be non-toxic, and form a bond with bone. In bone repair applications, i.e. scaffolds for bone regeneration, the solubility of bioceramics is an important parameter, and the slow dissolution rate of most bioceramics relative to bone growth rates remains a challenge in their remedial usage.
Micro-mass cultures of C3H-10T1/2 cells at varied oxygen tensions stained with Alcian blue. A commonly applied definition of tissue engineering, as stated by Langer [3] and Vacanti, [4] is "an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve [Biological tissue] function or a ...
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