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Levonorgestrel, also known as 17α-ethynyl-18-methyl-19-nortestosterone or as 17α-ethynyl-18-methylestr-4-en-17β-ol-3-one, is a synthetic estrane steroid and a derivative of testosterone. [ 63 ] [ 64 ] It is the C13β or levorotatory stereoisomer and enantiopure form of norgestrel , the C13α or dextrorotatory isomer being inactive.
Extended cycle use of COCPs may also be called menstrual suppression, [2] although other hormonal medications or medication delivery systems (hormonal intrauterine devices—IUDs) may also be used to suppress menses. Any brand of combined oral contraceptive pills can be used in an extended or continuous manner by simply discarding the placebo ...
The ovulation-inhibiting dosage of levonorgestrel, which is twice as potent as norgestrel, is approximately 50 to 60 μg/day. [6] [18] [17] One review lists the ovulation-inhibiting dose of norgestrel as 100 μg/day. [19]
OTC emergency contraception pills in the U.S. contain levonorgestrel, which is in a class of medications called progestins (which are a synthetic form of the hormone progesterone).
Norgestimate is a rapidly and completely converted prodrug, mainly of norelgestromin (17β-deacetylnorgestimate or levonorgestrel 3-oxime), but also of levonorgestrel (3-keto-17β-deacetylnorgestimate) to a lesser extent (22 ± 6% of an administered dose or about 40–70 μg) [2] and of levonorgestrel acetate (levonorgestrel 17β-acetate) in ...
All contain an estrogen, ethinylestradiol or mestranol, [1] [2] in varying amounts, and one of a number of different progestogens. (Regarding the estrogen, the inactive 3-methyl ether of ethinylestradiol, which must be metabolized by the liver into the active ethinylestradiol; 50 μg of mestranol is equivalent to only 35 μg of ethinylestradiol and should not be used when high-dose [50 μg ...
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