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The functional layer of the endometrial lining undergoes cyclic regeneration from stem cells in the basal layer. [1] Humans, apes, and some other species display the menstrual cycle , whereas most other mammals are subject to an estrous cycle . [ 2 ]
Vertical section of mucous membrane of human uterus. The uterus has three layers, which together form the uterine wall. From innermost to outermost, these layers are the endometrium, myometrium, and perimetrium. [7] The endometrium is the inner epithelial layer, along with its mucous membrane, of the mammalian uterus.
As the syncytiotrophoblast starts to penetrate the uterine wall, the inner cell mass (embryoblast) also develops. The inner cell mass is the source of embryonic stem cells, which are pluripotent and can develop into any one of the three germ layer cells, and which have the potency to give rise to all the tissues and organs.
The myometrium is located between the endometrium (the inner layer of the uterine wall) and the serosa or perimetrium (the outer uterine layer).. The inner one-third of the myometrium (termed the junctional or sub-endometrial layer) appears to be derived from the Müllerian duct, while the outer, more predominant layer of the myometrium appears to originate from non-Müllerian tissue and is ...
This layer is absent in placenta accreta. [2] Micrograph of decidualized endometrium due to exogenous progesterone. H&E stain. The decidua has a histologically-distinct appearance, displaying large polygonal decidual cells in the stroma. These are enlarged endometrial stromal cells, which resemble epithelium (and are referred to as "epithelioid").
The epiblast gives rise to the three germ layers of the developing embryo during gastrulation (endoderm, mesoderm, and ectoderm). The trophoblast is a layer of cells forming the outer ring of the blastocyst that combines with the maternal endometrium to form the placenta. Trophoblast cells also secrete factors to make the blastocoel. [25]
The inner cell mass will go on to become the actual embryo. The external, surrounding cells develop into trophoblast cells, which only contribute to extra-embryonic tissues. At this stage there is no lumen within the embryo. In a process called cavitation, trophectoderm cells transport fluid into the embryo to create a blastocoel, the fluid ...
It is the mass of cells inside the blastocyst that will eventually give rise to the definitive structures of the fetus. The inner cell mass forms in the earliest stages of embryonic development, before implantation into the endometrium of the uterus. [1] The ICM is entirely surrounded by the single layer of trophoblast cells of the trophectoderm.