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Evidence suggests that it is the interaction between genes and the environment may be associated with the development of schizophrenia. [2] This is a complex process involving multiple environmental factors that have influence on a range of developmental periods that interact with a genetic susceptibility. [7]
The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
The causes of schizophrenia may include genetic and environmental factors. [7] Genetic factors include a variety of common and rare genetic variants . [ 21 ] Possible environmental factors include being raised in a city , childhood adversity, cannabis use during adolescence, infections, the age of a person's mother or father , and poor ...
A study done over a two-year time period shadowing patients with schizophrenia and monitoring their depression was unable to locate possible triggers such as the ones previously listed, so it is possible the nature of schizophrenia itself is the primary cause of post-schizophrenic depression. [11]
Advanced, chronic schizophrenia can not respond even to clozapine, regarded as the most effective antipsychotic, [15] as such, a cure for highly advanced schizophrenia is likely impossible through the use of any modern antipsychotics, so the value of early intervention cannot be stressed enough.
About Schizophrenia Schizophrenia is a chronic, progressive and severely debilitating mental disorder that affects how one thinks, feels and acts. 2 Patients experience an array of symptoms, which may include delusions, hallucinations, disorganized speech or behavior, and impaired cognitive ability. 2,3,4 Approximately 1% of the world’s ...
Risk factors for mental illness include psychological trauma, adverse childhood experiences, genetic predisposition, and personality traits. [7] [8] Correlations between mental disorders and substance use are also found to have a two way relationship, in that substance use can lead to the development of mental disorders and having mental disorders can lead to substance use/abuse.
Psychosis is considered to be among the top 10 causes of social disability among adult men and women in developed countries. [172] The traditional, negative narrative around disability has been shown to adversely influence employment and education for people experiencing psychosis.
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