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Luspatercept is indicated for the treatment of adults with transfusion-dependent anemia due to very low, low and intermediate-risk myelodysplastic syndromes (MDS) with ring sideroblasts, who had an unsatisfactory response to or are ineligible for erythropoietin-based therapy.
A myelodysplastic syndrome (MDS) is one of a group of cancers in which blood cells in the bone marrow do not mature, and as a result, do not develop into healthy blood cells. [3] Early on, no symptoms typically are seen. [3] Later, symptoms may include fatigue, shortness of breath, bleeding disorders, anemia, or frequent infections. [3]
Luspatercept - phase III: On 28 August 2023, BMS' drug Reblozyl has received FDA label expansion, making it a first-line treatment option for anemia in adults with low- to intermediate-risk myelodysplastic syndromes (MDS) who may need regular blood transfusions.
Breast cancer was the only type for which treatment advances prevented more deaths. Quitting smoking was found to be the most beneficial prevention strategy overall, credited for averting 3.45 ...
Therapeutic, diagnostic and preventive monoclonal antibodies are clones of a single parent cell. When used as drugs, the International Nonproprietary Names (INNs) end in -mab.
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