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Neglected tropical diseases (NTDs) are a diverse group of tropical infections that are common in low-income populations in developing regions of Africa, Asia, and the Americas. [2] They are caused by a variety of pathogens , such as viruses , bacteria , protozoa , and parasitic worms ( helminths ).
Although neglected tropical diseases can be fatal, there is a lack of modern, safe and effective medications to treat these illnesses. [8] Evidence of the lack of new drugs for diseases that cause high mortality and morbidity among people living in poor areas has been published in the scientific literature. One publication reported that only 1. ...
The World Health Organization classified 20 major diseases as neglected tropical diseases (NTD), while finer classifications consider several additional conditions. [4] The diseases collectively had affected almost 2 billion people worldwide every year, causing about 200,000 deaths and almost 50 disability adjusted life years annually.
They must be knowledgeable in the 18 lesser known neglected tropical diseases, which include Chagas disease, rabies, and dengue. Poor living conditions in developing regions of tropical countries have led to a rising number of non-communicable diseases as well as the prevalence of neglected tropical diseases. These diseases include cancer and ...
In 1975 the Special Programme for Research and Training in Tropical Diseases (TDR) was established to focus on neglected infectious diseases which disproportionately affect poor and marginalized populations in developing regions of Africa, Asia, Central America and North South America.
The disease is the cause of decreased vision in 2.2 million people, of whom 1.2 million are completely blind. [2] Trachoma is a public health problem in 42 countries across Africa, Asia, the Middle East, and Central and South America. [7] There are 136.9 million people at risk. [2] It results in US$8 billion of economic losses a year. [2]
[60] [61] In East Africa, the WHO recommended treatment is SSG&PM (sodium stibogluconate and paromomycin) developed by Drugs for Neglected Diseases initiative (DNDi) in 2010. [62] Miltefosine is the first oral treatment for this disease. The cure rate of miltefosine in Phase III clinical trials is 95%; Studies in Ethiopia show that is also ...
The Global Network for Neglected Tropical Diseases is an advocacy initiative of the Sabin Vaccine Institute dedicated to raising the awareness, political will, and funding necessary to control and eliminate the most common Neglected Tropical Diseases (NTDs)—a group of disabling, disfiguring, and deadly diseases affecting more than 1.4 billion people worldwide living on less than $1.25 a day.