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  2. Thyroid hormones - Wikipedia

    en.wikipedia.org/wiki/Thyroid_hormones

    The thyroid hormones act on nearly every cell in the body. It acts to increase the basal metabolic rate, affect protein synthesis, help regulate long bone growth (synergy with growth hormone) and neural maturation, and increase the body's sensitivity to catecholamines (such as adrenaline) by permissiveness. [12]

  3. Iodothyronine deiodinase - Wikipedia

    en.wikipedia.org/wiki/Iodothyronine_deiodinase

    Activation occurs by conversion of thyroxine (T 4) to the active hormone triiodothyronine (T 3) through the removal of an iodine atom on the outer ring. Inactivation of thyroid hormones occurs by removal of an iodine atom on the inner ring, which converts thyroxine to the inactive reverse triiodothyronine (rT 3), or which converts the active ...

  4. Euthyroid sick syndrome - Wikipedia

    en.wikipedia.org/wiki/Euthyroid_sick_syndrome

    Three primary deiodinases are responsible for thyroid hormone conversion and breakdown. Type 1 (D1) deiodinates T4 to the biologically active T3, as well as the hormonally inactive and possibly inhibitory rT3. [3] [5] Type 2 (D2) converts T4 into T3, and breaks down rT3. D3 produces rT3 from T4, and breaks down T3.

  5. Thyroid-stimulating hormone - Wikipedia

    en.wikipedia.org/wiki/Thyroid-stimulating_hormone

    TSH (with a half-life of about an hour) stimulates the thyroid gland to secrete the hormone thyroxine (T 4), which has only a slight effect on metabolism. T 4 is converted to triiodothyronine (T 3), which is the active hormone that stimulates metabolism. About 80% of this conversion is in the liver and other organs, and 20% in the thyroid ...

  6. Liothyronine - Wikipedia

    en.wikipedia.org/wiki/Liothyronine

    Liothyronine is the most potent form of thyroid hormone. As a salt of triiodothyronine (T 3 ), it is chemically similar and pharmacologically equivalent to T 3 . As such, it acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body's sensitivity to catecholamines (such as adrenaline) by permissiveness .

  7. Deiodinase - Wikipedia

    en.wikipedia.org/wiki/Deiodinase

    Iodotyrosine deiodinase contributes to breakdown of thyroid hormones. It releases iodine , for renewed use, from iodinated tyrosines resulting from catabolism of iodothyronines. Iodotyrosine deiodinase employs a flavin mononucleotide cofactor and belongs to the NADH oxidase/flavin reductase superfamily.

  8. Common thyroid drug levothyroxine linked to bone mass loss - AOL

    www.aol.com/common-thyroid-drug-levothyroxine...

    Thyroid stimulating hormone (TSH) is produced by the pituitary gland, another hormone-producing organ in the head. This in turn causes the thyroid to produce T3 and T4, which play a role in the ...

  9. Diiodotyrosine - Wikipedia

    en.wikipedia.org/wiki/Diiodotyrosine

    DIT is a modulator of the enzyme thyroid peroxidase (which is involved in the production of thyroid hormones). [1] Triiodothyronine is formed, when diiodotyrosine is combined with monoiodotyrosine (in the colloid of the thyroid follicle). Two molecules of DIT combine to make the thyroid hormone thyroxine ('T4' and 'T3').

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