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  2. Hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism

    TSH values may also be lower than normal (particularly in the first trimester) and the normal range should be adjusted for the stage of pregnancy. [ 8 ] [ 44 ] In pregnancy, subclinical hypothyroidism is defined as a TSH between 2.5 and 10 mIU/L with a normal thyroxine level, while those with TSH above 10 mIU/L are considered to be overtly ...

  3. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    This may also be called standard range. In contrast, optimal (health) range or therapeutic target is a reference range or limit that is based on concentrations or levels that are associated with optimal health or minimal risk of related complications and diseases. For most substances presented, the optimal levels are the ones normally found in ...

  4. Hashimoto's thyroiditis - Wikipedia

    en.wikipedia.org/wiki/Hashimoto's_thyroiditis

    TSH is the preferred initial test of thyroid function as it has a higher sensitivity to changes in thyroid status than free T 4. [ 60 ] Time of day can affect the results of this test; TSH peaks early in the morning and slumps in the late afternoon to early evening, [ 61 ] with "a variation in TSH by a mean of between 0.95 mIU/mL to 2.0 mIU/mL ...

  5. Triiodothyronine - Wikipedia

    en.wikipedia.org/wiki/Triiodothyronine

    The compound migrated close to thyroxine in chromatography and they initially named it 'unknown 1' . Around that time a group led by Jean Roche in Paris described a deiodinating activity in the sheep thyroid gland, raising the possibility that 'unknown 1' is the less iodinated analogue of T4, triiodothyronine. [24]

  6. Levothyroxine - Wikipedia

    en.wikipedia.org/wiki/Levothyroxine

    Levothyroxine is also used to treat subclinical hypothyroidism, which is defined by an elevated TSH level and a normal-range free T 4 level without symptoms. [14] Such people may be asymptomatic [ 14 ] and whether they should be treated is controversial. [ 13 ]

  7. Reference range - Wikipedia

    en.wikipedia.org/wiki/Reference_range

    The standard definition of a reference range for a particular measurement is defined as the interval between which 95% of values of a reference population fall into, in such a way that 2.5% of the time a value will be less than the lower limit of this interval, and 2.5% of the time it will be larger than the upper limit of this interval, whatever the distribution of these values.

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  9. Iodine - Wikipedia

    en.wikipedia.org/wiki/Iodine

    The major form of thyroid hormone in the blood is tetraiodothyronine (T 4), which has a longer life than triiodothyronine (T 3). In humans, the ratio of T 4 to T 3 released into the blood is between 14:1 and 20:1. T 4 is converted to the active T 3 (three to four times more potent than T 4) within cells by deiodinases (5'-iodinase).