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Having less functional GLUT1 protein reduces the amount of glucose available to brain cells, which affects brain development and function. [14] Because glucose is the primary source of fuel for the brain, patients with GLUT1 deficiency have insufficient cellular energy to permit normal brain growth and function. [8]
A rare metabolic disease of the blood-brain glucose transport system has been described in which severe neuroglycopenic effects occurred despite normal blood glucose levels. Low levels of glucose were discovered in the cerebrospinal fluid (CSF), a condition referred to as hypoglycorrhachia [or hypoglycorrhacia].
n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human Glucose transporter 1 (or GLUT1), also known as solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), is a uniporter protein that in humans is encoded by the SLC2A1 gene. GLUT1 facilitates the transport of glucose across ...
For this study, called the DIRECT PLUS brain-MRI trial, researchers hypothesized that improved glycemic control—stable blood sugar—is a contributing factor to the brain-protecting effects of ...
Apr. 12—Type 1 diabetes patients showed slower and less accurate cognitive responses when their blood sugar levels were too low or high, according to a study that gives another reason for ...
The latest study suggests that improved blood sugar regulation might contribute to the neuroprotective effects of Mediterranean and green Mediterranean diets on brain aging.
However, elevated blood sugar levels (hyperglycemia) result in elevated CSF glucose levels [3] as the CSF glucose level is proportional to the blood glucose level with glucose being actively transported as well as simply diffusing down the concentration gradient from blood to CSF. In addition, damage to small blood vessels during lumbar ...
Artificial sweeteners do not lower blood sugar levels. [116] The blood sugar content of a healthy person in the short-time fasting state, e.g. after overnight fasting, is about 70 to 100 mg/dL of blood (4 to 5.5 mM). In blood plasma, the measured values are about 10–15% higher.