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  2. GABA receptor agonist - Wikipedia

    en.wikipedia.org/wiki/GABA_receptor_agonist

    Gamma-aminobutyric acid, a GABA-B receptor agonist. A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. [1] There are three receptors of the gamma-aminobutyric acid. The ...

  3. Insomnia affects up to 50% of adults and can hurt your body ...

    www.aol.com/finance/insomnia-affects-50-adults...

    Insomnia is one of the most common sleep disorders, with the Centers for Disease Control and Prevention reporting that as many as one in two adults experience short-term bouts, while one in 10 may ...

  4. Alcohol withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Alcohol_withdrawal_syndrome

    Insomnia can be difficult to treat in these individuals because many of the traditional sleep aids (e.g., benzodiazepine receptor agonists and barbiturate receptor agonists) work via a GABA A receptor mechanism and are cross-tolerant with alcohol.

  5. Effects of long-term benzodiazepine use - Wikipedia

    en.wikipedia.org/wiki/Effects_of_long-term...

    Significant toxicity from benzodiazepines can occur in the elderly as a result of long-term use. [112] Benzodiazepines, along with antihypertensives and drugs affecting the cholinergic system, are the most common cause of drug-induced dementia affecting over 10 percent of patients attending memory clinics.

  6. Do women need more sleep than men? Here’s what ... - AOL

    www.aol.com/women-more-sleep-men-experts...

    In addition to insomnia, women are more likely to experience other sleep disorders, like restless leg syndrome, which can compromise sleep quality. ... women can aim to get around 7.5 hours of ...

  7. Is This the Reason You Can't Sleep? New Study Reveals ... - AOL

    www.aol.com/reason-cant-sleep-study-reveals...

    A new study reveals a shocking potential cause for insomnia. ... The Guardian reports that one of the genes impacted by PFAS is the cathepsin B gene, which can create enzymes, when in high levels ...

  8. List of investigational sleep drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_investigational...

    Toggle Insomnia subsection. 1.1 GABA A receptor potentiators. 1.2 Orexin receptor antagonists. ... EVT-201 – GABA A receptor positive allosteric modulator

  9. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    Specifically, it is a derivative of GABA with a pentyl disubstitution at 3 position, hence, the name - gabapentin, in such a way as to form a six-membered ring. After the formation of the ring, the amine and carboxylic groups are not in the same relative positions as they are in the GABA; [103] they are more conformationally constrained. [104]

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