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In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs [1] that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. [ 2 ] [ 3 ] They are located on the left and right in the retroperitoneal space , and in adult humans are about 12 centimetres ( 4 + 1 ⁄ 2 inches) in ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 13 November 2024. This article is about the human urinary system. For urinary systems of other vertebrates, see Urinary systems of birds, urinary systems of reptiles, and urinary systems of amphibians. Anatomical system consisting of the kidneys, ureters, urinary bladder, and the urethra Urinary system 1 ...
Also, between classes of animals, the kidneys differ in shape and anatomical location. [9] [10] In mammals, they are usually bean-shaped. [11] Evolutionarily, the kidneys first appeared in fish as a result of the independent evolution of the renal glomeruli and tubules, which eventually united into a single functional unit. [12]
According to the Centers for Disease Control and Prevention, 15 percent of U.S. adults have chronic kidney disease, a health condition in which the kidneys can’t filter blood as well as they ...
The kidneys are located behind the peritoneum, in the retroperitoneum, outside the abdominal cavity. The viscera are also covered by visceral peritoneum . Between the visceral and parietal peritoneum is the peritoneal cavity , which is a potential space. [ 1 ]
Mammalian kidneys are susceptible to ischemic injury because mammals lack a renal-portal system, and as a result, vascular vasoconstriction in the glomeruli can lead to decreased blood supply to the entire kidney. The kidneys are susceptible to toxic injury, since toxins are reabsorbed in the tubules along with most of the filtered substances. [47]
The kidneys filter about 150 quarts (170 liters) of blood daily, but most of it is returned to the blood stream with only 1-2 quarts (1-2 liters) ending up as urine. [53] The urine is brought by the ureters from the kidneys down to the bladder .
The juxtaglomerular apparatus is part of the kidney nephron, next to the glomerulus. It is found between afferent arteriole and the thick ascending limb of the loop of Henle (distal straight tubule) of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. [2] [3]