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It contains ethinylestradiol, an estrogen, and etonogestrel, a progestin. [2] It is used by insertion into the vagina. [1] Pregnancy occurs in about 0.3% of women with perfect use and 9% of women with typical use. [3] Common side effects include irregular vaginal bleeding, nausea, sore breasts, vaginitis, mood changes, and headache. [4]
Irregular bleeding and spotting: Many women will experience some type of irregular, unpredictable, prolonged, frequent, or infrequent bleeding. [31] Some women also experience amenorrhea . For some women, prolonged bleeding will decline after the first three months of use.
Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body. They act by blocking the estrogen receptor (ER) and/or inhibiting or suppressing estrogen production .
This is the same as estrogen, and it’s used as a medication to manage and treat symptoms of menopause. Estradiol is the most common form of the estrogen hormone for hormone replacement therapy ...
Desogestrel is a hormone blocker, progesterone receptors agonist, and antiandrogen.It is used in conjunction with estrogens and testosterones.Medications containing desogestrel and estrogen are used to treat endometriosis [21] [29] and as a component of menopausal hormone therapy.
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DMPA can affect menstrual bleeding. After a year of use, 55% of women experience amenorrhea (missed periods); after two years, the rate rises to 68%. In the first months of use "irregular or unpredictable bleeding or spotting, or, rarely, heavy or continuous bleeding" was reported. [73]
For perfect use it is 99% effective and typical use is 91% effective. Side effects of the pill include headache, dizziness, nausea, sore breasts, spotting, mood changes, acne, bloating, etc. [clarification needed] One pill offers the benefit of only having to be taken once a week: Ormeloxifene, a selective estrogen receptor modulator