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7-Hydroxycannabidiol (7-OH-CBD) is an active metabolite of cannabidiol, generated in the body from cannabidiol by the action of the enzyme CYP2C19. [1] While methods have been developed for its synthetic production, [2] and measurement of levels in the body following consumption of cannabidiol, [3] its pharmacology has been relatively little studied, though it has been found to possess similar ...
Acute effects while under the influence can sometimes include euphoria or anxiety. [ 4 ] [ 5 ] Although some assert that cannabidiol (CBD), another cannabinoid found in cannabis in varying amounts, may alleviate the adverse effects of THC that some users experience, [ 6 ] little is known about CBD's effects on humans.
Abnormal cannabidiol (Abn-CBD) is a synthetic regioisomer of cannabidiol, which unlike most other cannabinoids produces vasodilator effects, lowers blood pressure, and induces cell migration, cell proliferation and mitogen-activated protein kinase activation in microglia, but without producing any psychoactive or sedative effects.
[4] [20] CBD does not have the same psychoactivity as THC, [25] [26] and can modulate the psychoactive effects of THC on the body if both are present. [17] [25] [27] [28] Conversion of CBD to THC can occur when CBD is heated to temperatures between 250–300 °C, potentially leading to its partial transformation into THC. [29]
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Candida albicans infection; Candida parapsilosis infection; Cytomegalovirus infection; diphtheria; human coronavirus infection; respiratory distress syndrome; measles; meconium aspiration syndrome
A 2012 review of cannabis use and dependency in the United States by Danovitch et al said that "42% of persons over age 12 have used cannabis at least once in their lifetime, 11.5% have used within the past year, and 1.8% have met diagnostic criteria for cannabis abuse or dependence within the past year. Among individuals who have ever used ...