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The effects of the toxicants depends on the dose, threshold and duration. The effects of toxicity are: Minor structural deformities - e.g. Anticonvulsant drugs, Warfarin, Retinoic Acid derivatives; Major structural deformities - e.g. DES (diethylstilbestrol), cigarette smoking; Growth Retardation - e.g. Alcohol, Polychlorinated Biphenyls
Substance abuse, also known as drug abuse, is the use of a drug in amounts or by methods that are harmful to the individual or others. It is a form of substance-related disorder . Differing definitions of drug abuse are used in public health , medical, and criminal justice contexts.
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
Drug addiction, which belongs to the class of substance-related disorders, is a chronic and relapsing brain disorder that features drug seeking and drug abuse, despite their harmful effects. [27] This form of addiction changes brain circuitry such that the brain's reward system is compromised, [ 28 ] causing functional consequences for stress ...
A psychoactive drug, mind-altering drug, or consciousness-altering drug is a chemical substance that changes brain function and results in alterations in perception, mood, consciousness, cognition, or behavior. [1] The term psychotropic drug is often used interchangeably, while some sources present narrower definitions.
A date rape drug, also called a predator drug, is any drug that can be used as incapacitating agent to assist in the execution of drug facilitated sexual assault (DFSA). The most common types of DFSA are those in which a victim ingested drugs willingly for recreational purposes, or had them administered surreptitiously: [ 30 ] it is the latter ...
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. [1] Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell (cytotoxicity) or an organ such as the liver (hepatotoxicity).
An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery. [1] An adverse effect may be termed a " side effect ", when judged to be secondary to a main or therapeutic effect .