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Oncotic pressure, or colloid osmotic-pressure, is a type of osmotic pressure induced by the plasma proteins, notably albumin, [1] in a blood vessel's plasma (or any other body fluid such as blood and lymph) that causes a pull on fluid back into the capillary.
The rate at which fluid is filtered across vascular endothelium (transendothelial filtration) is determined by the sum of two outward forces, capillary pressure and interstitial protein osmotic pressure (), and two absorptive forces, plasma protein osmotic pressure and interstitial pressure (). The Starling equation describes these forces in ...
The loss of protein can lead to edema, particularly in the legs and abdomen, due to decreased oncotic pressure. [4] Nutritional deficiencies may develop due to malabsorption, leading to growth retardation in children and weight loss in adults. [5] Immune abnormalities resulting from lymphocyte loss can predispose patients to recurrent ...
The normal ranges to check for the serum globulin would be about 2.0 to 3.5 grams per deciliter then for the immunoglobulins A, M, and G have different ranges. If there are abnormal results then there are different possibilities on what it could mean either there is an acute infection, long-term inflammatory diseases, or Waldenström ...
Lower serum oncotic pressure causes fluid to accumulate in the interstitial tissues. Sodium and water retention aggravates the edema. This may take several forms: Puffiness around the eyes, characteristically in the morning. Pitting edema over the legs. Fluid in the pleural cavity causing pleural effusion. More commonly associated with excess ...
The low protein theory for the pathogenesis of kwashiorkor has been used to teach that capillary exchange between the lymphatic system and circulating blood is impaired by a reduced oncotic (i.e. colloid osmotic pressure, COP) in the blood, as a consequence of inadequate protein intake, so that the hydrostatic pressure gradient, which favors ...
Children have greater compensatory mechanisms than adults and can maintain a normal blood pressure despite considerable loss of fluid. For example, a child with sepsis or severe dehydration may seem unaffected and the acute condition is often identified only by the affected vital parameters. [13]
11657 Ensembl ENSG00000163631 ENSMUSG00000029368 UniProt P02768 P07724 RefSeq (mRNA) NM_000477 NM_009654 RefSeq (protein) NP_000468 NP_033784 Location (UCSC) Chr 4: 73.4 – 73.42 Mb Chr 5: 90.61 – 90.62 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Human serum albumin is the serum albumin found in human blood. It is the most abundant protein in human blood plasma ; it ...