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2. Protein primary structure - Wikipedia

   en.wikipedia.org/wiki/Protein_primary_structure

   Knowing the structure of a similar homologous sequence (for example a member of the same protein family) allows highly accurate prediction of the tertiary structure by homology modeling. If the full-length protein sequence is available, it is possible to estimate its general biophysical properties, such as its isoelectric point.

3. Homology modeling - Wikipedia

   en.wikipedia.org/wiki/Homology_modeling

   Homology model of the DHRS7B protein created with Swiss-model and rendered with PyMOL. Homology modeling, also known as comparative modeling of protein, refers to constructing an atomic-resolution model of the "target" protein from its amino acid sequence and an experimental three-dimensional structure of a related homologous protein (the "template").

4. Sequence space (evolution) - Wikipedia

   en.wikipedia.org/wiki/Sequence_space_(evolution)

   Each round of selection samples mutants on all sides of the starting template (1) and selects the mutant with the highest elevation, thereby climbing the hill. This is repeated until a local summit is reached (2). In evolutionary biology, sequence space is a way of representing all possible sequences (for a protein, gene or genome).

5. Sequence analysis - Wikipedia

   en.wikipedia.org/wiki/Sequence_analysis

   However, comparing these new sequences to those with known functions is a key way of understanding the biology of an organism from which the new sequence comes. Thus, sequence analysis can be used to assign function to coding and non-coding regions in a biological sequence usually by comparing sequences and studying similarities and differences.

6. Threading (protein sequence) - Wikipedia

   en.wikipedia.org/wiki/Threading_(protein_sequence)

   After the best-fit template is selected, the structural model of the sequence is built based on the alignment with the chosen template. Protein threading is based on two basic observations: that the number of different folds in nature is fairly small (approximately 1300); and that 90% of the new structures submitted to the PDB in the past three ...

7. Template:Protein sequence - Wikipedia

   en.wikipedia.org/wiki/Template:Protein_sequence

   Template for producing a stretch of protein sequence. Adds CSS class aa-sequence. Template parameters

8. Protein sequencing - Wikipedia

   en.wikipedia.org/wiki/Protein_sequencing

   Protein sequence interpretation: a scheme new protein to be engineered in a yeast. It is often desirable to know the unordered amino acid composition of a protein prior to attempting to find the ordered sequence, as this knowledge can be used to facilitate the discovery of errors in the sequencing process or to distinguish between ambiguous results.

9. Biomolecular structure - Wikipedia

   en.wikipedia.org/wiki/Biomolecular_structure

   The primary structure of a biopolymer is the exact specification of its atomic composition and the chemical bonds connecting those atoms (including stereochemistry).For a typical unbranched, un-crosslinked biopolymer (such as a molecule of a typical intracellular protein, or of DNA or RNA), the primary structure is equivalent to specifying the sequence of its monomeric subunits, such as amino ...