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Oxygenation zones are numbered inside the diamond-shaped acinus (in red). Zone three is closest to the central vein and zone one is closest to the portal triad. Zones differ by function: zone I hepatocytes are specialized for oxidative liver functions such as gluconeogenesis, β-oxidation of fatty acids and cholesterol synthesis
The hepatic artery provides 30 to 40% of the oxygen to the liver, while only accounting for 25% of the total liver blood flow. The rest comes from the partially deoxygenated blood from the portal vein. The liver consumes about 20% of the total body oxygen when at rest.
The kidneys secrete a variety of hormones, including erythropoietin, calcitriol, and renin. Erythropoietin is released in response to hypoxia (low levels of oxygen at tissue level) in the renal circulation. It stimulates erythropoiesis (production of red blood cells) in the bone marrow.
The adjective renal, meaning related to the kidney, is from the Latin rēnēs, meaning kidneys; the prefix nephro-is from the Ancient Greek word for kidney, nephros (νεφρός). [37] For example, surgical removal of the kidney is a nephrectomy , while a reduction in kidney function is called renal dysfunction .
All vertebrates have kidneys. The kidneys are the main organ that allows species to adapt to different environments, including fresh and salt water, terrestrial life and desert climate. [7] Depending on the environment in which animals have evolved, the functions and structure of the kidneys may differ. [8]
The nephron is the functional unit of the kidney. [3] This means that each separate nephron is where the main work of the kidney is performed. A nephron is made of two parts: a renal corpuscle, which is the initial filtering component, and; a renal tubule that processes and carries away the filtered fluid. [4]: 1024
The key to increasing your longevity is believed to be found in these five regions of the world
The solid organs are the liver, pancreas, spleen, kidneys, and adrenal glands. The hollow organs of the abdomen are the stomach , intestines , gallbladder , bladder , and rectum . [ 6 ] In the thoracic cavity , the heart is a hollow, muscular organ. [ 7 ]