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In general, biological aging clocks and biomarkers of aging are expected to find many uses in biological research since age is a fundamental characteristic of most organisms. Accurate measures of biological age (biological aging clocks) could be useful for testing the validity of various theories of biological aging,
The free-radical theory of aging proposes that this damage cumulatively degrades the biological function of cells and impacts the process of aging. [18] The idea that free radicals are toxic agents was first proposed by Rebeca Gerschman and colleagues in 1945, [19] but came to prominence in 1956, when Denham Harman proposed the free-radical ...
Overview, including some physiological parameters, of the human circadian rhythm ("biological clock"). Chronobiology is a field of biology that examines timing processes, including periodic (cyclic) phenomena in living organisms, such as their adaptation to solar- and lunar-related rhythms. [1] These cycles are known as biological rhythms.
While we can test biological age for some insights into how well someone is aging, for now, the best way to stay healthy is to keep up to date with screenings and follow the evidence-based ...
As women age, ovarian reserve -- which is defined as the quantity and the quality of the eggs remaining in the ovaries -- declines, and when all eggs are depleted, menopause starts and ...
The metabolic stability theory of aging suggests it is the cells ability to maintain stable concentration of ROS which is the primary determinant of lifespan. [37] This theory criticizes the free radical theory because it ignores that ROS are specific signalling molecules which are necessary for maintaining normal cell functions. [37]
Examples include circannual or annual cycles that govern migration or reproduction cycles in many plants and animals, or the human menstrual cycle. Ultradian rhythms , which are cycles shorter than 24 hours, such as the 90-minute REM cycle , the 4-hour nasal cycle , or the 3-hour cycle of growth hormone production.
Circadian clock, a molecular mechanism that results in a circadian rhythm in a living organism; Circadian rhythm, biological process that displays an oscillation about 24 hours, such as the human sleep-wake cycle (the "body clock") Epigenetic clock, a set of DNA sites whose methylation levels can be used to measure aging throughout the body