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Metformin itself isn’t thought to cause hair loss, but type 2 diabetes and PCOS (polycystic ovary syndrome) — the conditions it’s prescribed to treat — can cause hair loss.
Metformin: Metformin works for weight loss by reducing insulin resistance, improving glycemic control and decreasing appetite. It’s especially helpful for people with conditions like PCOS or ...
“Well-managed PCOS after weight loss can help improve symptoms, but under severe stress, women with this condition are predisposed to developing the condition again, along with being at risk for ...
Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom and not the underlying cause of the disorder.
It is more common in women than men. [4] Symptoms of hyperandrogenism may include acne, seborrhea, hair loss on the scalp, increased body or facial hair, and infrequent or absent menstruation. [1] [2] Complications may include high blood cholesterol and diabetes. [4] It occurs in approximately 5% of women of reproductive age. [2]
[11] [12] Weight loss also generally results in improved menstrual regularity and pregnancy rates in women with PCOS. [13] It is well recognized that insulin resistance can be part of the sequelae of PCOS and if present, contribute to anovulation. Metformin, a biguanide, is a common insulin sensitizer often given to treat women with PCOS. [10]
2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.
For those who after weight loss still are anovulatory or for anovulatory lean women, ovulation induction to reverse the anovulation is the principal treatment used to help infertility in PCOS. Letrozole and Clomiphene citrate are the first-line treatment in subfertile anovulatory patients with PCOS. [12]