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Hypopharyngeal cancer is an uncommon cancer that develops in your lower throat behind your voice box. Symptoms may include hoarseness, sore throat and ear pain that doesn’t go away after two weeks. Treatments include surgery, chemotherapy, radiation therapy and immunotherapy.
After someone is diagnosed with hypopharyngeal cancer, doctors will try to figure out if it has spread, and if so, how far. This process is called staging. The stage of a cancer describes how much cancer is in the body. It helps determine how serious the cancer is and how best to treat it.
Laryngopharyngectomy and neck dissection has been the most frequently used therapy for hypopharyngeal cancers. In very selected cases of pyriform sinus cancers, that is, those arising in the upper lateral wall, a partial laryngopharyngectomy may be successfully used to preserve vocal function.
Nasal tumors begin in the main passageway within the nose, called the nasal cavity. Paranasal tumors begin in air-filled chambers around the nose, called the paranasal sinuses. Some nasal and paranasal tumors aren't cancerous. These noncancerous tumors also are called benign tumors.
The location within the sinus determines the surgical treatment options for cancers of the pyriform sinus. Early tumors of the lateral wall can be managed with partial pharyngectomy with partial resection of the lateral thyroid cartilage, particularly the upper ala.
Hypopharyngeal cancers are often named for their location, including pyriform sinus, lateral pharyngeal wall, posterior pharyngeal wall, or postcricoid pharynx (see images below). Most arise in...
Hypopharyngeal cancer is a rare cancer that begins in the hypopharynx, which is the bottom section of the throat. Experts consider it a type of head and neck cancer. It does not include cancers...
Hypopharyngeal squamous cell carcinoma (HPSCC) accounts for 3–5% of all head and neck cancers, and approximately 60–85% of patients with HPSCC patients have stages III–IV disease at the time of diagnosis [1, 2, 3] and thus demonstrate poor prognosis irrespective of contemporary aggressive multidisciplinary treatments [4].
However, radical surgery with total laryngectomy still plays an important role in the management of patients with hypopharyngeal carcinoma, either as the primary treatment modality (T4 resectable primary tumor, contraindication to larynx preservation therapies) or, more commonly, as salvage treatment.
Abstract. Hypopharyngeal carcinoma is uncommon in all head and neck cancers. With a synergistic reaction of each, tobacco consumption and alcohol abuse contribute to the tumorigenesis. The aerodigestive tract epithelium exposure to similar risks causing multiple cancers.