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Phytohaemagglutinin (PHA, or phytohemagglutinin) is a lectin found in plants, especially certain legumes. PHA actually consists of two closely related proteins, called leucoagglutinin (PHA-L) and PHA-E. These proteins cause blood cells to clump together. PHA-E cause erythrocytes (red blood cells) to clump.
For example, raw kidney beans naturally contain toxic levels of lectin (e.g. phytohaemagglutinin). Adverse effects may include nutritional deficiencies, ...
The toxic compound phytohaemagglutinin, a lectin, is present in many common bean varieties but is especially concentrated in red kidney beans. White kidney beans contain about a third as many toxins as the red variety; broad beans ( Vicia faba ) contain 5 to 10% as much as red kidney beans.
Phytohaemagglutinin, a toxic lectin, is present in many varieties of common bean but is especially concentrated in red kidney beans. The lectin has several effects on cell metabolism; it induces mitosis and affects the cell membrane regarding transport and permeability to proteins.
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Pokeweed mitogen has the ability to play a role in immunology.It can test for immunodeficiency by inducing cell proliferation and test for abnormal counts of lymphocytes. [2]
Illustration showing influenza virus attaching to cell membrane via the surface protein hemagglutinin. Hemagglutinins (alternatively spelt haemagglutinin, from the Greek haima, 'blood' + Latin gluten, 'glue') are homotrimeric glycoproteins present on the protein capsids of viruses in the Paramyxoviridae and Orthomyxoviridae families.
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