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The cell nucleus (from Latin nucleus or nuculeus ' kernel, seed '; pl.: nuclei) is a membrane-bound organelle found in eukaryotic cells.Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells, have no nuclei, and a few others including osteoclasts have many.
The cytoplasm describes all the material within a eukaryotic or prokaryotic cell, enclosed by the cell membrane, including the organelles [1] and excluding the nucleus in eukaryotic cells. The material inside the nucleus of a eukaryotic cell and contained within the nuclear membrane is termed the nucleoplasm .
The nucleus is spherical and separated from the cytoplasm by a double membrane called the nuclear envelope, space between these two membrane is called perinuclear space. The nuclear envelope isolates and protects a cell's DNA from various molecules that could accidentally damage its structure or interfere with its processing.
Claims for older DNA have been made, most notably a report of the isolation of a viable bacterium from a salt crystal 250 million years old, [150] but these claims are controversial. [151] [152] Building blocks of DNA (adenine, guanine, and related organic molecules) may have been formed extraterrestrially in outer space.
Nucleoplasm is quite similar to the cytoplasm, with the main difference being that nucleoplasm is found inside the nucleus while the cytoplasm is located inside the cell, outside of the nucleus. Their ionic compositions are nearly identical due to the ion pumps and permeability of the nuclear envelope, however, the proteins in these two fluids ...
The nuclear envelope is studded by a great number of nuclear pores that give access to various molecules, to and from the nucleoplasm and the cytoplasm. Small molecules can diffuse easily but other larger molecules need to be transported across. [1] The nuclear pore complex consists predominantly of proteins known as nucleoporins (Nups).
The cytosol consists mostly of water, dissolved ions, small molecules, and large water-soluble molecules (such as proteins). The majority of these non-protein molecules have a molecular mass of less than 300 Da. [11]
Association and maturation of rRNA and r-proteins result in the formation of the 40S (small) and 60S (large) subunits of the complete ribosome. These are exported through the nuclear pore complexes to the cytoplasm, where they remain free or become associated with the endoplasmic reticulum, forming the rough endoplasmic reticulum (RER). [20] [21]