Search results
Results from the WOW.Com Content Network
Pomalidomide, sold under the brand names Pomalyst and Imnovid, [7] [8] is an anti-cancer medication used for the treatment of multiple myeloma and AIDS-related Kaposi sarcoma. [ 7 ] Pomalidomide was approved for medical use in the United States in February 2013, [ 10 ] and in the European Union in August 2013. [ 8 ]
The thalidomide molecule is a synthetic derivative of glutamic acid and consists of a glutarimide ring and a phthaloyl ring (Figure 5). [15] [16] Its IUPAC name is 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione and it has one chiral center [15] After thalidomide's selective inhibition of TNF-α had been reported, a renewed effort was put in thalidomide's clinical development.
Many such groupings include one or more of a monoclonal antibody (e.g., isatuximab or daratumumab), an immunomodulatory agent (e.g., lenalidomide or pomalidomide), and a proteasome inhibitor (e.g., or bortezomib, carfilzomib or ixazomib), in combination with a steroid (e.g., dexamethasone).
Hasan is proof that you’re not destined to lose all your muscle and strength if you decide to go on a weight loss medication. You just have to be smart about your nutrition and training.
If you lose too many electrolytes (such as through sweating) or drink excessive amounts of plain water without replenishing them, it can dilute the sodium in your blood, leading to a condition ...
Whether you're healthy and trying to fend off the flu or unwell and wanting to nip a runny nose, you might consider a natural remedy like elderberry. Elderberries are rich in anti-inflammatory and ...
Lenalidomide is used to treat multiple myeloma. [11] It is a more potent molecular analog of thalidomide, which inhibits tumor angiogenesis, tumor-secreted cytokines, and tumor proliferation through induction of apoptosis.
English: Skeletal formulae of two enantiomers of pomalidomide (brand names Pomalyst and Imnovid) — (R)-(+)- and (S)-(−)-pomalidomide. This medication is used in the third-line treatment of multiple myeloma. Created with ChemDoodle 7.0.2 and Adobe Illustrator CC 2015.